Physical and Biochemical Properties

[ Nomenclature | Morphology & Structure | Symptoms & Host | Property | Genome | Reference ]

Properties of particles in sap
    TIP: 45-50 . LIV: 10 days (at 4 Centigrade). DEP: log10 minus 3-4 (in sap from rice leaves). Infectivity of sap not changed by treatment with di-ethyl ether. Leaf sap contains many virions.
Purification method
    N/A
Particle morphology
    Virions isometric; not enveloped; 70 nm in diameter; angular in profile; with a conspicuous capsomere arrangement.
Physical properties
    Two sedimenting components in purified preparations; sedimentation coefficient 510 S. Density 1.26 g cm-3 in CsCl (T), or 1.38 g cm-3 in CsCl (M1), or 1.43 g cm-3 in CsCl (M2), or 1.46 g cm-3 in CsCl (B). A260/A280 ratio 1.4.
Biochemical properties
    Virions contain 20 % nucleic acid; 80 % protein.
    Genome consists of RNA; double-stranded; linear. Total genome size 25.13 kb (pairs). Genome of 12 parts (named S1-12); largest genome part 4.354 kb (pairs); the 2nd largest 3.385 kb (pairs); the 3rd largest 3.195 kb (pairs); the 4th largest 2.468 kb (pairs); the 5th largest 2.57 kb (pairs); the 6th largest and other parts 1.699 kb (pairs); also 1.696, 1.424, 1.305, 1.319, 0.887 and 0.828 kb pairs). Genomic nucleic acid isolated by Kimura et al. Base composition 21.8-22.8 % G; 27.8-28.4 % A; 21.4-21.6 % C; 28-28.2 % U. Base composition of ds genome 42.3-48.1 % (G + C). 5กไ terminus of RNA has an unusual type; shows the sequence of GGCA or GGUA. Infectivity lost when deproteinised with phenol or detergent. Poly A region absent.

Antigenic Properties

Serological Relationships
    Virus(es) with serologically related virions: rice gall dwarf virus. Virus(es) with serologically unrelated virions: clover wound tumour virus. Each segment has a high homology with corresponding segments of clover wound tumour and rice gall dwarf viruses.
Diagnosis
    Best tests for diagnosis: distinguish by characteristic symptoms and serological tests.

Last Modified: Nov. 1999 cbi@pku.edu.cn