Potential Synergy Mapping at a Short Distance between Upstream Region and Intron of Yeast Highly-transcribed Genes
Introduction
Our previous work suggested that introns of yeast genes likely regulate the transcription efficiencies of genes. One possible way that introns regulate the transcription efficiencies is to cooperate with upstream region. To explore this mechanism, we still selected the two sets of yeast gene with opposite biological feature, one set is highly-transcribed (>=30 mRNAs/hr) and the other set is lowly-transcribed (<= 10 mRNAs/hr). We extracted the potential motifs of both upstream regions and introns of yeast highly-transcribed gene by our own novel statistical comparative method. Then a new method is employed to detect these motif pairs with potential synergy. To see the synergy clearly, all of the potential tetra-, penta-nucleotides (motifs) and synergy motif pairs are mapped to the 30 gene sequences. (See links below)
Synergy mapping
Potential motifs
Potential synergy motif pairs
- Original highly-transcribed genes sequences (including upstream regions and introns, text format)
- Original lowly-transcribed genes sequences (including upstream regions and introns, text format).
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