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Ge Gao, Ph.D.

Principal Investigator
Center for Bioinformatics
State Key Laboratory of Protein and Plant Gene Research
Life Science College
Peking University

Contact

E-mail: gaog_At_mail_dot_cbi_dot_edu_dot_pku_dot_cn
Tel: +86 10 6275 1861
Fax: +86 10 6275 1861

Address

Room 601
New Life Science Building
Peking University
Beijing, P. R. China,
100871

Research Interesting

Publications

Bioinformatics tools for mining and integrating high-throughput data

  1. Wang, J., Kong, L., Zhao, S., Zhang, H., Tang, L., Li, Z., Gu, X., Luo, J., and Gao, G.. 2011. Rice-Map: a new-generation rice genome browser. BMC Genomics 12: 165.
  2. Zhang, H., Jin, J., Tang, L., Zhao, Y., Gu, X., Gao, G., and Luo, J. 2010. PlantTFDB 2.0: update and improvement of the comprehensive plant transcription factor database. Nucleic Acids Research 39(Database issue): D1114-1117.
  3. Liu, X., Wu, J., Wang, J., Zhao, S., Li, Z., Kong, L., Gu, X., Luo, J., and Gao, G. 2009. WebLab: a data-centric, knowledge-sharing bioinformatic platform. Nucleic Acids Res 37(Web Server issue): W33-39.
  4. Zhao, S.Q., Wang, J., Zhang, L., Li, J.T., Gu, X., Gao, G., and Wei, L. 2009. BOAT: Basic Oligonucleotide Alignment Tool. BMC Genomics 10 Suppl 3: S2.
  5. Zhao, M., Chen, X., Gao, G., Tao, L., and Wei, L. 2009. RLEdb: a database of rate-limiting enzymes and their regulation in human, rat, mouse, yeast and E. coli. Cell Res 19(6): 793-795.
  6. Guo, A.Y., Chen, X., Gao, G., Zhang, H., Zhu, Q.H., Liu, X.C., Zhong, Y.F., Gu, X., He, K., and Luo, J. 2008. PlantTFDB: a comprehensive plant transcription factor database. Nucleic Acids Res 36(Database issue): D966-969.
  7. Sun, Y., Zhao, S., Yu, H., Gao, G., and Luo, J. 2007. ABCGrid: Application for Bioinformatics Computing Grid. Bioinformatics 23(9): 1175-1177.
  8. Kong, L., Zhang, Y., Ye, Z.Q., Liu, X.Q., Zhao, S.Q., Wei, L., and Gao, G. 2007. CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res 35(Web Server issue): W345-349.
  9. Ye, Z.Q., Zhao, S.Q., Gao, G., Liu, X.Q., Langlois, R.E., Lu, H., and Wei, L. 2007. Finding new structural and sequence attributes to predict possible disease association of single amino acid polymorphism (SAP). Bioinformatics 23(12): 1444-1450.
  10. Zhang, Y., Li, J., Kong, L., Gao, G., Liu, Q.R., and Wei, L. 2007. NATsDB: Natural Antisense Transcripts DataBase. Nucleic Acids Res 35(Database issue): D156-161.
  11. Zhu, Q.H., Guo, A.Y., Gao, G., Zhong, Y.F., Xu, M., Huang, M., and Luo, J. 2007. DPTF: a database of poplar transcription factors. Bioinformatics 23(10): 1307-1308.
  12. Gao, G., Zhong, Y., Guo, A., Zhu, Q., Tang, W., Zheng, W., Gu, X., Wei, L., and Luo, J. 2006. DRTF: a database of rice transcription factors. Bioinformatics 22(10): 1286-1287.

Function and evolution of novel regulators in early development

  1. Chen, Z., Zhang, Y., Vibranovski, M.D., Wei, L., Luo, J., Gao, G., Long, M. Deficiency of the X-linked inverted duplicates with male-biased expression and the underlying evolutionary mechanisms in the Drosophila genome. Molecular Biology and Evolution (in press)
  2. Liu, M., Liu, P., Zhang, L., Cai, Q. Gao, G., Zhang, W., Zhu, Z. Liu, D. Fan, Q. 2011. mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans. Cell Res (Epub ahead of print)
  3. Shen, L., Gao, G., Zhang, Y., Zhang. H., Ye, Z.Q., Huang, S., Huang, J. and Kang, J. 2010. A single amino acid substitution confers enhanced methylation activity of mammalian Dnmt3b on chromatin DNA. Nucleic Acids Res 38(18): 6054-6064.
  4. Gao, G., Li, J.T., Kong, L., Tao, L., and Wei, L. 2009. Human herpesvirus miRNAs statistically preferentially target host genes involved in cell signaling and adhesion/junction pathways. Cell Res 19(5): 665-667.
  5. Li, Z., Zhang, H., Ge, S., Gu, X., Gao, G., and Luo, J. 2009. Expression pattern divergence of duplicated genes in rice. BMC Bioinformatics 10(Suppl 6): S8.
  6. Li, Z., Liu, M., Zhang, L., Zhang, W., Gao, G., Zhu, Z., Wei, L., Fan, Q., and Long, M. 2009. Detection of intergenic non-coding RNAs expressed in the main developmental stages in Drosophila melanogaster. Nucleic Acids Res 37(13): 4308-4314.
  7. Ren, L., Gao, G., Zhao, D., Ding, M., Luo, J., and Deng, H. 2007. Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation. Genome Biol 8(3): R35.

Early Publications (before 2006)

  1. Chen Y, Zhang Y, Yin Y, Gao G, Li S, Jiang Y, Gu X, Luo J: SPD--a web-based secreted protein database. Nucleic Acids Res 2005, 33(Database issue):D169-173.
  2. Zhang Y, Yin Y, Chen Y, Gao G, Yu P, Luo J, Jiang Y: PCAS--a precomputed proteome annotation database resource. BMC Genomics 2003, 4(1):42.
  3. Jiang Y, Gao G, Fang G, Gustafson EL, Laverty M, Yin Y, Zhang Y, Luo J, Greene JR, Bayne ML et al: PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm Genome 2003, 14(5):341-349.
  4. Chen YJ, Gao G, Bao YM, Lopez R, Wu JM, Cai T, Ye ZQ, Gu XC, Luo JC: [Initial analysis of complete genome sequences of SARS coronavirus]. Yi Chuan Xue Bao 2003, 30(6):493-500.
  5. Gao G, Wu X, He K, Liu D, Yu P, Luo J: BiDMAP-A Biological Data Management and Analysis Platform. Computer Engineering 2002, 28(z1):145-153.
  6. 高歌 赵树起, 孔雷, 吴健民, 李哲, 唐汶, 罗静初: 高性能计算在基因组数据分析中的应用. 中国计算机学会通讯2006, 2(3):28-33.
  7. 孔雷, 高歌, 吴健民, 李哲, 赵树起, 唐汶, 罗静初: 基于Linux的生物信息操作环境. 中国计算机学会通讯 2006, 2(3):57-61.
  8. 方刚, 陈蕴佳, 高歌, 刘翟, 何坤, 吴昕, 顾孝诚, 罗静初: 基因组数据库简介. 遗传 2003, 25(4):440-444.